Directions:
If you are traveling by ferry from Bari, Ancona, Brindisi, or Venice, the four main ports of Italy, you will arrive at the city of Igoumenitsa, on the West coast of Greece. Once in Igoumenitsa, proceed in the direction of the city of Ioannina. From Ioannina, head towards the cities of Kalambaka and Trikala and then on to the city of Larissa. From Larissa, you will turn North onto the Thessaloniki-Athens Highway ("National Highway 1" or "European Highway E-75" which is the same highway), with direction towards Thessaloniki. (Total traveling distance from Igoumenitsa to Thessaloniki is 452 Km or about 6 hours. It may seem long, but the scenery through mountainous Greece is well worth it, believe us.)
Alternatively, from Italy, you may reach the southern Greek port of Patras, instead of Igoumenitsa. If so, use a map to the following course: From Patras (taking the road to Athens), to Rio, crossing to Antirio (via car ferry), on to Amfissa and then Lamia, where you will join the Athens-Thessaloniki Highway, turning North to Thessaloniki. (The Patras to Thessaloniki drive is 488 Km or about 6 hours, including the ferry time.)
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